Coronavirus: Dexamethasone proves first life-saving drug – BBC

Coronavirus: Dexamethasone proves first life-saving drug – BBC

The low-dose steroid treatment dexamethasone is a major breakthrough in the fight against the deadly virus, UK experts say.

 

A cheap and widely available drug can help save the lives of patients seriously ill with coronavirus.

The drug is part of the world’s biggest trial testing existing treatments to see if they also work for coronavirus.

It cut the risk of death by a third for patients on ventilators. For those on oxygen, it cut deaths by a fifth.

Had the drug had been used to treat patients in the UK from the start of the pandemic, up to 5,000 lives could have been saved, researchers say.

And it could be of huge benefit in poorer countries with high numbers of Covid-19 patients.

About 19 out of 20 patients with coronavirus recover without being admitted to hospital. Of those who are admitted to hospital, most also recover, but some may need oxygen or mechanical ventilation. These are the high-risk patients whom dexamethasone appears to help.

The drug is already used to reduce inflammation in a range of other conditions, and it appears that it helps stop some of the damage that can happen when the body’s immune system goes into overdrive as it tries to fight off coronavirus.

The body’s over-reaction is called a cytokine storm and it can be deadly.

Chart showing effect on patients on ventilators and requiring oxygen
Presentational white space

In the trial, led by a team from Oxford University, around 2,000 hospital patients were given dexamethasone and were compared with more than 4,000 who did not receive the drug.

For patients on ventilators, it cut the risk of death from 40% to 28%. For patients needing oxygen, it cut the risk of death from 25% to 20%.

Chief investigator Prof Peter Horby said: “This is the only drug so far that has been shown to reduce mortality – and it reduces it significantly. It’s a major breakthrough.”

Lead researcher Prof Martin Landray says the findings suggest that for every eight patients treated on ventilators, you could save one life.

For those patients treated with oxygen, you save one life for approximately every 20-25 treated with the drug.

“There is a clear, clear benefit. The treatment is up to 10 days of dexamethasone and it costs about £5 per patient. So essentially it costs £35 to save a life. This is a drug that is globally available.”

Prof Landray said, when appropriate, hospital patients should now be given it without delay, but people should not go out and buy it to take at home.

Dexamethasone does not appear to help people with milder symptoms of coronavirus – those who don’t need help with their breathing.

The Recovery Trial has been running since March. It included the malaria drug hydroxychloroquine which has subsequently been ditched amid concerns that it increases fatalities and heart problems.

Another drug called remdesivir, an antiviral treatment that appears to shorten recovery time for people with coronavirus, is already being made available on the NHS.

Presentational grey line
Analysis box by Fergus Walsh, health correspondent

The first drug proven to cut deaths from Covid-19 is not some new, expensive medicine but an old, cheap-as-chips steroid.

That is something to celebrate because it means patients across the world could benefit immediately. That’s why the top-line results of this trial have been rushed out – because the implications are so huge globally.

Dexamethasone has been used since the early 1960s to treat a wide range of conditions, such as rheumatoid arthritis and asthma. Half of all Covid patients who require a ventilator do not survive, so cutting that risk by a third would have a huge impact.

The drug is given intravenously in intensive care, and in tablet form for less seriously ill patients. So far, the only other drug proven to benefit Covid patients is remdesivir, an antiviral treatment which has been used for Ebola.

That has been shown to reduce the duration of coronavirus symptoms from 15 days to 11, but the evidence was not strong enough to show whether it reduced mortality. Unlike dexamethasone, remdesivir is a new drug with limited supplies and a price has yet to be announced.

Source: BBC

Sometimes you just have to ask yourself: WHAT ARE THE CHANCES OF THAT ? – #watcot

 

Support WATCOT.org

  • Bitcoin
  • Ethereum
  • Xrp
  • Bitcoin cash
  • Bitcoin sv
  • Litecoin
  • Tether
  • Eos
  • Binance coin
  • Tezos
  • Cardano
  • Dash
  • Nem
  • Monero
  • Stellar
  • Ethereum classic
  • Lisk
  • Tron
  • Neo
  • Vechain
  • Qtum
  • Omisego
  • Icon
  • Nano
  • Zcash
  • Ontology
Scan to Donate Bitcoin to bc1qgkhtgufrz6wsczamwkl0dwk0fa8uq45m2zr75l

Donate Bitcoin to this address

Scan the QR code or copy the address below into your wallet to send some Bitcoin

Scan to Donate Ethereum to 0x203E3D9Ad868699316bEac2D0F31F4236c002a3E

Donate Ethereum to this address

Scan the QR code or copy the address below into your wallet to send some Ethereum

Scan to Donate Xrp to rH79rmr7T66wm1ka4o9xDG4m1Nzi1QR8Y

Donate Xrp to this address

Scan the QR code or copy the address below into your wallet to send some Xrp

Scan to Donate Bitcoin cash to qr8lggv04m2f4ehfa2dr8fwcymuhnp6mvc7npefp2s

Donate Bitcoin cash to this address

Scan the QR code or copy the address below into your wallet to send some Bitcoin cash

Scan to Donate Bitcoin sv to 12aRp4BSe1uX9DjKtUEjXAQGJZzSzEsfjP

Donate Bitcoin sv to this address

Scan the QR code or copy the address below into your wallet to send some Bitcoin sv

Scan to Donate Litecoin to LgTyhWBmcMbzsJ9jUBsVNdTwiApyPRcbaV

Donate Litecoin to this address

Scan the QR code or copy the address below into your wallet to send some Litecoin

Scan to Donate Tether to 0x203E3D9Ad868699316bEac2D0F31F4236c002a3E

Donate Tether to this address

Scan the QR code or copy the address below into your wallet to send some Tether

Scan to Donate Eos to rH79rmr7T66wm1ka4o9xDG4m1Nzi1QR8Y

Donate Eos to this address

Scan the QR code or copy the address below into your wallet to send some Eos

Tag/Note:- XRP Adress
Scan to Donate Binance coin to bnb1rl86hrnk99jpnac8zas6lcy9sakh40q6037kn6

Donate Binance coin to this address

Scan the QR code or copy the address below into your wallet to send some Binance coin

Scan to Donate Tezos to tz1drWpwUFnXMCNk2fP41Tj2ejo5dpcbepno

Donate Tezos to this address

Scan the QR code or copy the address below into your wallet to send some Tezos

Scan to Donate Cardano to Ae2tdPwUPEZ6JE1RCBBCsKUHXoxaSzciykxBxn7M7mkEaC9k9A1Wjz4Mmiu

Donate Cardano to this address

Scan the QR code or copy the address below into your wallet to send some Cardano

Scan to Donate Dash to XnPa4jjZyj9oWLm2kpVq1EnAFzcEDJEmae

Donate Dash to this address

Scan the QR code or copy the address below into your wallet to send some Dash

Scan to Donate Nem to NDHYY5NBOAITXNWGJOEHHFLDNJROEF33Q4DGSMX6

Donate Nem to this address

Scan the QR code or copy the address below into your wallet to send some Nem

Scan to Donate Monero to 48tCYZezTBMSY4JhjqtpkjMnGK5YZmuFdHgFLLayn33H1TJ9MkbFN9gSxxpxN9okn15HHUcCpeAqE3e319fxYjipVghBr9R

Donate Monero to this address

Scan the QR code or copy the address below into your wallet to send some Monero

Scan to Donate Stellar to GA3PAAWGWN6NDEXI7TPEJMXXHBCGA77LDMBWSIVBVENFAYT2KF6BJCB5

Donate Stellar to this address

Scan the QR code or copy the address below into your wallet to send some Stellar

Scan to Donate Ethereum classic to 0x08BB2f0c85dB4cD298b397be87b65b0300230C10

Donate Ethereum classic to this address

Scan the QR code or copy the address below into your wallet to send some Ethereum classic

Scan to Donate Lisk to 4554698783447062922L

Donate Lisk to this address

Scan the QR code or copy the address below into your wallet to send some Lisk

Scan to Donate Tron to TEfQHuDBQs4uebJFGQxVE861KzMk4Go1nV

Donate Tron to this address

Scan the QR code or copy the address below into your wallet to send some Tron

Scan to Donate Neo to AS2XK5bXq8vM2uXUMvjFm5THP7SnmG7bLq

Donate Neo to this address

Scan the QR code or copy the address below into your wallet to send some Neo

Scan to Donate Vechain to 0x4c560ADb0dd96eF16ACC9b9974d4114472BE772a

Donate Vechain to this address

Scan the QR code or copy the address below into your wallet to send some Vechain

Scan to Donate Qtum to Qj7tBabQdbUbdKyoeytnehe9dddbzyRjbb

Donate Qtum to this address

Scan the QR code or copy the address below into your wallet to send some Qtum

Scan to Donate Omisego to 0x203E3D9Ad868699316bEac2D0F31F4236c002a3E

Donate Omisego to this address

Scan the QR code or copy the address below into your wallet to send some Omisego

Scan to Donate Icon to hxc90d401693c7244df9fc5f9b425b11dcbd17b385

Donate Icon to this address

Scan the QR code or copy the address below into your wallet to send some Icon

Scan to Donate Nano to nano_1kmmfcukewa53s66eeeh5reyfu9zyxrggchs1pug6grdk4jjsjp7h5m7mskc

Donate Nano to this address

Scan the QR code or copy the address below into your wallet to send some Nano

Scan to Donate Zcash to t1dsg9VUBKHB8yKoNhufFWnjafiqEt6GxgX

Donate Zcash to this address

Scan the QR code or copy the address below into your wallet to send some Zcash

Scan to Donate Ontology to AdkmjPehgcqDHDnjTtiwsgH1FkimViyfPS

Donate Ontology to this address

Scan the QR code or copy the address below into your wallet to send some Ontology

Categories

Somtimes you just have to ask youself.

WHAT ARE THE CHANCES OF THAT? - #watcot

All donations go to supporting the team and infrastructure that is needed in order to bring you the truth, all content has been verified. We will continue to bring you the evidence to allow you to make up your own minds and ask yourself. 

What are the chances of that? #WATCOT

  • Bitcoin
  • Ethereum
  • Xrp
  • Bitcoin cash
  • Bitcoin sv
  • Litecoin
  • Tether
  • Eos
  • Binance coin
  • Tezos
  • Cardano
  • Dash
  • Nem
  • Monero
  • Stellar
  • Ethereum classic
  • Lisk
  • Tron
  • Neo
  • Vechain
  • Qtum
  • Omisego
  • Icon
  • Nano
  • Zcash
  • Ontology
Scan to Donate Bitcoin to bc1qgkhtgufrz6wsczamwkl0dwk0fa8uq45m2zr75l

Donate Bitcoin to this address

Scan the QR code or copy the address below into your wallet to send some Bitcoin

Scan to Donate Ethereum to 0x203E3D9Ad868699316bEac2D0F31F4236c002a3E

Donate Ethereum to this address

Scan the QR code or copy the address below into your wallet to send some Ethereum

Scan to Donate Xrp to rH79rmr7T66wm1ka4o9xDG4m1Nzi1QR8Y

Donate Xrp to this address

Scan the QR code or copy the address below into your wallet to send some Xrp

Scan to Donate Bitcoin cash to qr8lggv04m2f4ehfa2dr8fwcymuhnp6mvc7npefp2s

Donate Bitcoin cash to this address

Scan the QR code or copy the address below into your wallet to send some Bitcoin cash

Scan to Donate Bitcoin sv to 12aRp4BSe1uX9DjKtUEjXAQGJZzSzEsfjP

Donate Bitcoin sv to this address

Scan the QR code or copy the address below into your wallet to send some Bitcoin sv

Scan to Donate Litecoin to LgTyhWBmcMbzsJ9jUBsVNdTwiApyPRcbaV

Donate Litecoin to this address

Scan the QR code or copy the address below into your wallet to send some Litecoin

Scan to Donate Tether to 0x203E3D9Ad868699316bEac2D0F31F4236c002a3E

Donate Tether to this address

Scan the QR code or copy the address below into your wallet to send some Tether

Scan to Donate Eos to rH79rmr7T66wm1ka4o9xDG4m1Nzi1QR8Y

Donate Eos to this address

Scan the QR code or copy the address below into your wallet to send some Eos

Tag/Note:- XRP Adress
Scan to Donate Binance coin to bnb1rl86hrnk99jpnac8zas6lcy9sakh40q6037kn6

Donate Binance coin to this address

Scan the QR code or copy the address below into your wallet to send some Binance coin

Scan to Donate Tezos to tz1drWpwUFnXMCNk2fP41Tj2ejo5dpcbepno

Donate Tezos to this address

Scan the QR code or copy the address below into your wallet to send some Tezos

Scan to Donate Cardano to Ae2tdPwUPEZ6JE1RCBBCsKUHXoxaSzciykxBxn7M7mkEaC9k9A1Wjz4Mmiu

Donate Cardano to this address

Scan the QR code or copy the address below into your wallet to send some Cardano

Scan to Donate Dash to XnPa4jjZyj9oWLm2kpVq1EnAFzcEDJEmae

Donate Dash to this address

Scan the QR code or copy the address below into your wallet to send some Dash

Scan to Donate Nem to NDHYY5NBOAITXNWGJOEHHFLDNJROEF33Q4DGSMX6

Donate Nem to this address

Scan the QR code or copy the address below into your wallet to send some Nem

Scan to Donate Monero to 48tCYZezTBMSY4JhjqtpkjMnGK5YZmuFdHgFLLayn33H1TJ9MkbFN9gSxxpxN9okn15HHUcCpeAqE3e319fxYjipVghBr9R

Donate Monero to this address

Scan the QR code or copy the address below into your wallet to send some Monero

Scan to Donate Stellar to GA3PAAWGWN6NDEXI7TPEJMXXHBCGA77LDMBWSIVBVENFAYT2KF6BJCB5

Donate Stellar to this address

Scan the QR code or copy the address below into your wallet to send some Stellar

Scan to Donate Ethereum classic to 0x08BB2f0c85dB4cD298b397be87b65b0300230C10

Donate Ethereum classic to this address

Scan the QR code or copy the address below into your wallet to send some Ethereum classic

Scan to Donate Lisk to 4554698783447062922L

Donate Lisk to this address

Scan the QR code or copy the address below into your wallet to send some Lisk

Scan to Donate Tron to TEfQHuDBQs4uebJFGQxVE861KzMk4Go1nV

Donate Tron to this address

Scan the QR code or copy the address below into your wallet to send some Tron

Scan to Donate Neo to AS2XK5bXq8vM2uXUMvjFm5THP7SnmG7bLq

Donate Neo to this address

Scan the QR code or copy the address below into your wallet to send some Neo

Scan to Donate Vechain to 0x4c560ADb0dd96eF16ACC9b9974d4114472BE772a

Donate Vechain to this address

Scan the QR code or copy the address below into your wallet to send some Vechain

Scan to Donate Qtum to Qj7tBabQdbUbdKyoeytnehe9dddbzyRjbb

Donate Qtum to this address

Scan the QR code or copy the address below into your wallet to send some Qtum

Scan to Donate Omisego to 0x203E3D9Ad868699316bEac2D0F31F4236c002a3E

Donate Omisego to this address

Scan the QR code or copy the address below into your wallet to send some Omisego

Scan to Donate Icon to hxc90d401693c7244df9fc5f9b425b11dcbd17b385

Donate Icon to this address

Scan the QR code or copy the address below into your wallet to send some Icon

Scan to Donate Nano to nano_1kmmfcukewa53s66eeeh5reyfu9zyxrggchs1pug6grdk4jjsjp7h5m7mskc

Donate Nano to this address

Scan the QR code or copy the address below into your wallet to send some Nano

Scan to Donate Zcash to t1dsg9VUBKHB8yKoNhufFWnjafiqEt6GxgX

Donate Zcash to this address

Scan the QR code or copy the address below into your wallet to send some Zcash

Scan to Donate Ontology to AdkmjPehgcqDHDnjTtiwsgH1FkimViyfPS

Donate Ontology to this address

Scan the QR code or copy the address below into your wallet to send some Ontology